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℡ 4000-520-616
℡ 4000-520-616
genlantis/BioPORTER® Protein Delivery Reagent/FITC Antibody Control 10 ul, ABFITC01 $95FITC Antibody Control 6 x 10 ul, ABFITC06 $404 (+309)
市  场 价:¥1900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: genlantis
公      司:genlantis
公司分类:
genlantis/BioPORTER® Protein Delivery Reagent/FITC Antibody Control 10 ul, ABFITC01 $95FITC Antibody Control 6 x 10 ul, ABFITC06 $404 (+309)
商品介绍
Description
Data
Literature
Citations
  • Efficient protein delivery into a wide variety of cell types
  • 2X more effective than electroporation
  • Efficient delivery of a variety of proteins, peptides, and other macromolecules
  • Fast and Easy Protocol

BioPORTER® Protein Delivery Reagent is a unique lipid formulation that allows direct translocation of proteins into living cells. BioPORTER Protein Delivery kits provide researchers with a quick and easy method to study protein function without the need for cloning and DNA transfection. After capturing the protein, the reagent transports the lipid protein complex into the target cell. The delivered proteins retain their structure and function while leaving the transduced cells unharmed. The reagent is especially useful when studying protein function in cells that are difficult to transfect using traditional DNA protein transfection reagents.

ContentsBioPORTER kits are available as either a bulk reagent or as pre-dispensed and dried in convenient single-use QuikEase vials.

  • Dry BioPORTER Protein Delivery Reagent (1 vial for Cat. No. BP502401, 4 vials for Cat. No. BP509604, 24 single use vials for Cat. No. BP502424, 96 single-use vials for Cat. No. BP509696)
  • β-galactosidase Control Protein (1 vial x 10 μg)
    FITC-labeled Goat IgG Control Protein (1 vial x 10 μg)
  • StorageBioPORTER Protein Delivery Reagent kits are shipped frozen. For maximum stability, store all biological reagents and components at -20ºC upon receipt. The reagent is stable for 1 year when stored at the recommended temperature.

    BioPORTER Protein Delivery Kit
    • 24 rxn kit, BP502401
    • 24 single-use tubes kit, BP502424
    • 96 rxn kit, BP509604
    • 96 single-use tubes kit, BP509696
    • FITC Antibody Control 10 ul, ABFITC01
    • FITC Antibody Control 6 x 10 ul, ABFITC06
    • B-gal Control Protein 10 ul, BGALCP01
    • B-gal Control Protein 6 x 10 ul, BGALCP06

    Patents pending

    New Citations Correction of Impaired Calmodulin Binding to Ryr2 as a Novel Therapy of Lethal Arrhythmia in the Pressure-Overloaded Heart Failure Nakamura, Y.,et al (2016) HRS 14(1): 120-127. Link

    Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24 Yoshida, M.,et al (2016) Am. J. Physiol. Gastrointest. Liver Physiol. 310(8): G586–G59. Link

    The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES Guo, J.L.,et al (2016) J. Biol. Chem. 291(25): 13175–13193. Link

    High Affinity CaM, but Not Normal Affinity CaM Can Prevent Arrhythmias in CPVT Which Mutation is Located at CaM-like Domain of RyR2Nishimura, S.,et al (2015) AHA 132(3): 2967-2978 Link

    Host Cell Plasma Membrane Phosphatidylserine Regulates the Assembly and Budding of Ebola VirusAdu-Gyamfi, E.,et al (2015) J. Virol. 89(18): 9440-945. Link

    Cytotoxicity of Human Endogenous RetrovirusK–Specific T Cells toward Autologous Ovarian Cancer CellsRycaj, K.,et al (2014) Clin. Cancer Res. 21(2): 471–8 Link

    Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein PathologyMichel, C.H.,et al (2014) J. Biol. Chem.289(2): 956 –96. Link

    AAA Peroxins and Their Recruiter Pex26p Modulate the Interactions of Peroxins Involved in Peroxisomal Protein ImportTamura, S.,et al (2014) J. Biol. Chem. 289(35): 24336 –24346. Link

    Dissociation of Calmodulin From RyR2 Causes Diastolic Ca2+ leak and Induces Lethal Arrhythmias in Pressure-overload Heart FailureKato, T.,et al (2014) AHA 130(2): 1524-1539. Link

    Inhibition of rhBMP-2-induced ALP activity by intracellular delivery of SMURF1 in murine calvarial preosteoblast cellsHsu, C.W.,et al (2014) J. Biomed. Mater. Res. 102(11):4037-4043 Link

    BioPORTER Protein Delivery Reagent Cell Line Citations: A549, B16-F0, BHK-21, BN16, C2C12, C6, CA9-22, Calu-3, CHO-K1, Cos-1, COS-7, HCN2A, HEK 293, HeLa, HeLa-S3, HepG2, Heu127, HL60, HLE-B3, Huh-7, HUVEC, Jurkat, K562, Ki-Ras 267, LNCaP, MEG-01,NIH-3T3, OK, Osteosarcoma Cell Line, PC-12, Primary Cortical Neurons, Primary Pancreatic Islets of Langerhans Epithelial beta Cells, Primary Neutrophils, Primary LEC, Primary Polymorphonuclear Leukocytes, Primary Neutrophils, Primary Adventitial Fibroblasts, Primary Cardiac Myocytes, Primary Vascular Smooth Muscle Cells, Primary Ventricular Muscle, Primary Cortical Neurons, Primary Astroglia Capillary Endothelial Cells, Primary AML, Primary Bronchial Epithelial Cells, Primary CML, Primary Cortical Neurons, Primary Eye Lens Epithelium, Primary Microvascular Endothelial Cells, Primary Neutrophils, Primary Retina, Primary Retinal Growth Cone, rBCEC4, SH-SY5Y, UM-SCC-23

    BioPORTER® Protein Delivery Kit provides researchers with a quick and easy method to study protein function without the need for cloning and DNA transfection. BioPORTER® reagent lipid captures proteins and transports them inside the target cells. The delivered proteins retain their structure and function while leaving the transduced cells unharmed. BioPORTER® kit is especially useful when studying protein function in cells that are difficult to transfect using traditional DNA transfection reagents.

    For additional speed and convenience, The BioPORTER Reagent product line is also available in pre-coated single-use BioPORTER® QuikEase™ tubes. QuikEase tubes save hours of time by eliminating the need to coat the BioPORTER Reagent onto individual vials.

    BP502401-509604 BioPORTER® Manual (pdf)BP502424-BP509696 BioPORTER® QuikEase Manual (pdf)BP502401-509604 BioPORTER® Brochure (pdf)BP502401-509604 BioPORTER® Citations (pdf)BP502401-509604 BioPORTER® Data (pdf)BP502401-509604 BioPORTER® FAQs (pdf)
    Cell Line Cell Type Source Genlantis Product Citation
    A549 Lung Carcinoma Human BioPORTER Protein Delivery Reagent Anestal, K. and Arnéér, E.S.J. (2003) Rapid induction of cell death by selenium compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine. J. Biol. Chem: 278: 15966 - 15972.
    A549 Lung Carcinoma Human BioPORTER Protein Delivery Reagent Haince, J-F., Kozlov, S., Dawson, V.L., Dawson, T.M., Hendzel, M.J., Lavin, M.F. and Poirier, G.G. (2007) Ataxia Telangiectasia Mutated (ATM) Signaling Network Is Modulated by a Novel Poly(ADP-ribose)-dependent Pathway in the Early Response to DNA-damaging Agents. J. Biol. Chem. 282: 16441-16453.
    B16-F0 Melanoma Mouse BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    BHK-21 Kidney Fibroblast Hamster BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    BN16 Yolk Sac Carcinoma Rat BioPORTER Protein Delivery Reagent Nagai, J., Christensen, E. I., Morris, S. M., Willnow, T. E., Cooper, J. A. and Nielsen, R. (2005) Mutually dependent localization of megalin and Dab2 in the renal proximal tubule. AJP: Renal; 289(3): p. F569-F576. (Delivery of IgG into BN16)
    C2C12 Myoblast Mouse BioPORTER Protein Delivery Reagent Casciola-Rosen, L., Garcia-Calvo, M., Bull, H.G., Becker, J.W., Hines, T., Thornberry, N.A. and Rosen, A. (2007) Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the Bid pathway. J Biol Chem 282: 4545 - 4552. (Granzyme B delivery)
    C2C12 Myoblast Mouse BioPORTER Protein Delivery Reagent Fernando, P., Kelly, J.F., Balazsi, K., Slack, R.S., and Megeney, L.A. (2002) Caspase 3 activity is required for skeletal muscle differentiation Proc. Natl. Acad. Sci. 99: 11025 - 11030.
    C6 Glioma Rat BioPORTER Protein Delivery Reagent Zassler, B., Blasig, IE and Humpel, C. (2005) Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells. J Neurooncol. 71(2): p. 127.
    CA9-22 Gingival Squamous Cell Carcinoma Human BioPORTER Protein Delivery Reagent Yamamoto, K., Tominaga, K., Sukedai, M., Okinaga, T., Iwanaga, K., Nishihara, T. and Fukuda, J. (2004) Delivery of cytolethal distending toxin B induces cell cycle arrest and apoptosis in gingival squamous cell carcinoma in vitro. Eur J Oral Sci 112(5): p. 445.
    Calu-3 Lung Adenocarcinoma Human BioPORTER Protein Delivery Reagent Liedtke, C.M., Hubbard, M. and Wang, X. (2003) Stability of actin cytoskeleton and PKC-? binding to actin regulate NKCC1 function in airway epithelial cells. Am J Physiol Cell Physiol 284: 487 - 496.
    Calu-3 Lung Adenocarcinoma Human BioPORTER Protein Delivery Reagent Liedtke, C.M., Raghuram, V., Yun, C.C. and Wang, X. (2004) Role of a PDZ1 domain of NHERF1 in the binding of airway epithelial RACK1 to NHERF1. AJP: Cell 286(5): p. C1037-C1044.
    Calu-3 Lung Adenocarcinoma Human BioPORTER Protein Delivery Reagent Smallwood, N.D., Hausman, B.S., Wang, X. and Liedtke, C.M. (2005) Involvement of N-terminus of PKC{delta} in binding to F-actin during activation of Calu-3 airway epithelial NKCC1. AJP: Cell 288: 906 - 912.
    CHO-K1 Ovary Chinese Hamster BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    CHO-K1 Ovary Chinese Hamster BioPORTER Protein Delivery Reagent Zheng, X., Lundberg, M., Karlsson, A. and Johansson, M. (2003) Lipid-mediated protein delivery of suicide nucleoside kinases. Cancer Res. 63: 6909-6913.
    Cos-1 Kidney Green Monkey BioPORTER Protein Delivery Reagent Clegg, J.S. (2007) Protein Stability in Artemia Embryos During Prolonged Anoxia. Biol. Bull. 212(1): p. 74-81.
    COS-1 Kidney Green Monkey BioPORTER Protein Delivery Reagent Collins, CH and Clegg, JS (2004)¿A small heat-shock protein, p26, from the crustacean Artemia protects mammalian cells (Cos-1) against oxidative damage. Cell Biol Int 1 28(6): p. 449.
    COS-7 Kidney Green Monkey BioPORTER Protein Delivery Reagent Braun, A., Pinyol, R., Dahlhaus, R., Koch, D., Fonarev, P., Grant, B.D., Kessels, M.M. and Qualmann, B. (2005) EHD Proteins Associate with Syndapin I and II and Such Interactions Play a Crucial Role in Endosomal Recycling Mol. Biol. Cell. 16(8): p. 3642-3658. (Delivery of IgG)
    COS-7 Kidney Green Monkey BioPORTER Protein Delivery Reagent Fenster, S.D., Kessels, M.M., Qualmann, B., Chung, W.J., Nash, J., Gundelfinger, E.D. and Garner, C.C. (2003) Interactions between Piccolo and the actin/dynamin-binding protein Abp1 link vesicle endocytosis to presynaptic active zones. J. Biol. Chem. 278: 20268.
    COS-7 Kidney Green Monkey BioPORTER Protein Delivery Reagent Kessels, M.M. and Qualmann, B. (2002) Syndapins integrate N-WASP in receptor-mediated endocytosis. EMBO J. 21: 6083 - 6094.
    Cos-7 Kidney Green Monkey BioPORTER Protein Delivery Reagent Marques, C., Guo, W., Pereira, P., Taylor, A., Patterson, C., Evans, P.C. and Shang, F. (2006) The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones. FASEB J. 20(6):741-3.
    HCN2A Cortical Neurons Human BioPORTER Protein Delivery Reagent Shimura, H., Miura-Shimura, Y. and Kosik, K.S. (2004) Binding of Tau to Heat Shock Protein 27 Leads to Decreased Concentration of Hyperphosphorylated Tau and Enhanced Cell Survival. J. Biol. Chem. 279(17): p. 17957-17962
    HEK 293 Embryonic Kidney Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103  35110.
    HeLa Cervical Carcinoma Human BioPORTER Protein Delivery Reagent Fortugno, P., Wall, N.R., Giodini, A., O"Connor, D.S., Plescia, J., Padgett, K.M., Tognin, S., Marchisio, P.C. and Altieri, D.C. (2002) Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J. Cell Sci. 115: 575 - 585.
    HeLa-S3 Cervical Carcinoma Human BioPORTER Protein Delivery Reagent Fortugno, P., Beltrami, E., Plescia, J., Fontana, J., Pradhan, D., Marchisio, P.C., Sessa, W.C. and Altieri, D.C. (2003) Regulation of survivin function by Hsp90. PNAS 100: 13791 - 13796.
    HeLa-S3 Cervical Carcinoma Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    HepG2 Hepatocellular Carcinoma Human BioPORTER Protein Delivery Reagent Shao, H., Cheng, HY, Cook, R.G. and Tweardy, DJ (2003) Identification and Characterization of Signal Transducer and Activator of Transcription 3 Recruitment Sites within the Epidermal Growth Factor Receptor. Cancer Res 63: 3923.
    Heu127 T-Cell Lymphoma Human BioPORTER Protein Delivery Reagent Thiery, J., Dorothée, G., Haddada, H., Echchakir, H., Richon, C., Stancou, R., Vergnon, I., Benard, J., Mami-Chouaib, F. and Chouaib, S. (2003) Potentiation of a Tumor Cell Susceptibility to Autologous CTL Killing by Restoration of Wild-Type p53 Function. J. Immunol. 170: 5919 - 5926.
    HL60 Acute Myeloid Leukemia Human BioPORTER Protein Delivery Reagent McGrath, M.S., Rosenblum, M.G., Philips, M.R. and Scheinberg, D.A. (2003) Immunotoxin Resistance in Multidrug Resistant Cells. Cancer Res. 63: 72 - 79.
    HLE-B3 Lens Epithelial Cells Human BioPORTER Protein Delivery Reagent Fernando, M.R., Lechner, J.M., Lofgren, S., Gladyshev, V.N. and Lou, M.F. (2006) Mitochondrial thioltransferase (glutaredoxin 2) has GSH-dependent and thioredoxin reductase-dependent peroxidase activities in vitro and in lens epithelial cells FASEB J. 20(14): p. 2645-2647. (Delivery of Human Grx2, β-galactosidase, catalase)
    Huh-7 Hepatoma Human BioPORTER Protein Delivery Reagent Rabe, B., Glebe, D. and Kann, M. (2006) Lipid-mediated introduction of hepatitis B virus capsids into nonsusceptible cells allows highly efficient replication and facilitates the study of early infection events. J Virol 80(11): p. 5465.
    HUVEC Umbilical Vein Endothelial Human BioPORTER Protein Delivery Reagent Kakoki, M., Kim, H-S, Edgell, C-J.S., Maeda, N., Smithies, O. and Mattson, D.L. (2006) Amino acids as modulators of endothelium-derived nitric oxide. Am. J. Physiol. Renal Physiol. 291(2): F297-F304.
    Jurkat T-Cell Lymphoma Human BioPORTER Protein Delivery Reagent Azuma, Y., Kurusu, Y., Sato, H., Higai, K. and Matsumoto, K. (2007) Increased Expression of Lewis X and Y Antigens on the Cell Surface and FUT 4 mRNA during Granzyme B -Induced Jurkat Cell Apoptosis. Biol Pharm Bull 30(4): p. 655.
    Jurkat T-Cell Lymphoma Human BioPORTER Protein Delivery Reagent Casciola-Rosen, L., Garcia-Calvo, M., Bull, H.G., Becker, J.W., Hines, T., Thornberry, N.A. and Rosen, A. (2007) Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the Bid pathway. J Biol Chem 282: 4545 - 4552.
    Jurkat T-Cell Lymphoma Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    K562 Chronic Myeloid Leukemia Human BioPORTER Protein Delivery Reagent Hostetter, D.R., Loeb, C.R.K., Chu, F. and Craik, C.S. (2007) Hip Is a Pro-survival Substrate of Granzyme B. J. Biol. Chem. 282(38): 27865-27874.
    Ki-Ras 267? Prostate Epithelium Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    LNCaP Prostate Cancer Human BioPORTER Protein Delivery Reagent Loeb, C.R.K., Harris, J.L. and Craik, C.S. (2006) Granzyme B Proteolyzes Receptors Important to Proliferation and Survival, Tipping the Balance toward Apoptosis. J. Biol. Chem. 281(38): 28326-28335.
    MEG-01 Megakaryocyte Human BioPORTER Protein Delivery Reagent Clarke, M.C.H., Savill, J., Jones, D.B., Noble, B.S. and Brown, S.B. (2003) Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death J. Cell Biol. 160: 577 - 587.
    NIH-3T3 Fibroblast Mouse BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    NIH-3T3 Fibroblast Mouse BioPORTER Protein Delivery Reagent Zhao, R., Fu, X., Teng, L., Li, Q. and Zhao, Z.J. (2003) Blocking the Function of Tyrosine Phosphatase SHP-2 by Targeting Its Src Homology 2 Domains. J. Biol Chem. 278: 42893-42898.
    OK Kidney Opossum BioPORTER Protein Delivery Reagent Khundmiri, S.J., Dean, W.L., McLeish, K.R. and Lederer, E.D. (2005) Parathyroid Hormone-mediated Regulation of Na+-K+-ATPase Requires ERK-dependent Translocation of Protein Kinase C{alpha}. J. Biol. Chem. 280(10): p. 8705-8713.
    Osteosarcoma Cell Line Osteosarcoma Not Identified BioPORTER Protein Delivery Reagent Zheng, X., Lundberg, M., Karlsson, A. and Johansson, M. (2003) Lipid-mediated protein delivery of suicide nucleoside kinases. Cancer Res. 63: 6909-6913.
    PC-12 Pheochromocytoma Rat BioPORTER Protein Delivery Reagent Anantharam, V., Kitazawa, M., Wagner, J., Kaul, S., and Kanthasamy, A.G., (2002) Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase C Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl. J. Neurosci. 22:1738 - 1751.
    PC-12 Pheochromocytoma Rat BioPORTER Protein Delivery Reagent Gil, G.A., Bussolino, D.F., Portal, M.M., Pecchio, A.A., Renner, M.L., Borioli, G.A., Guido, M.E. and Caputto, B.L. (2004) c-Fos Activated Phospholipid Synthesis Is Required for Neurite Elongation in Differentiating PC12 Cells.Mol. Biol. Cell 15: 1881 - 1894.
    PC-12 Pheochromocytoma Rat BioPORTER Protein Delivery Reagent Kanno, T., Yamamoto, H., Yaguchi, T., Hi, R., Mukasa, T., Fujikawa, H., Nagata, T., Yamamoto, S., Tanaka, A. and Nishizaki, T. (2006) The newly synthesized linoleic acid derivative DCP-LA selectively activates PKC-epsilon possibly by binding to the phosphatidylserine binding site J. Lipid Res. 47: 1146-1156.
    PC-12 Pheochromocytoma Rat BioPORTER Protein Delivery Reagent Murakami, Y., Aizu-Yokota, E., Sonoda, Y., Ohta, S. and Kasahara, T. (2007) Suppression of Endoplasmic Reticulum Stress-induced Caspase Activation and Cell Death by the Overexpression of Bcl-xL or Bcl-2. J. Biochem. (Tokyo). 141(3): p. 401-410. (Antibody Delivery)
    Primary Cortical Neurons Mouse BioPORTER Protein Delivery Reagent Andrabi, S.A., Kim, N.S., Yu, S-W, Wang, H., Koh, D.W., Sasaki, M., Klaus, J.A., Otsuka, T., Zhang, Z., Koehler, R.C., Hurn, P.D., Poirier, G.G., Dawson, V.L. and Dawson, T.M. (2006) Poly(ADP-ribose) (PAR) polymer is a death signal. Proc. Natl. Acad. Sci. 103: 18308 - 18313.
    Primary Pancreatic Islets of Langerhans Epithelial beta Cells Syrian Golden Hamster BioPORTER Protein Delivery Reagent Cheng, H., Grodnitzky, J.A., Yibchok-anun, S., Ding, J. and Hsu, W.H. (2005) Somatostatin Increases Phospholipase D Activity and Phosphatidylinositol 4,5-bisphosphate Synthesis in Clonal {beta} Cells HIT-T15. Mol. Pharmacol. 67(6): p. 2162-2172.
    Primary Neutrophils Human BioPORTER Protein Delivery Reagent Fessler, M.B., Arndt, P.G., Just, I., Nick, J.A., Malcolm, K.C. and Worthen, G.S. (2007) Dual role for RhoA in suppression and induction of cytokines in the human Neutrophil. Blood 109: 1248 - 1256.
    Primary LEC Mouse BioPORTER Protein Delivery Reagent Lofgren, S., Fernando, M.R., Xing, K., Wang, Y., Kuszynski, C.A., Ho, Y. and Lou, M.F. (2008) Effect of Thioltransferase (Glutaredoxin) Deletion on Cellular Sensitivity to Oxidative Stress and Cell Proliferation in Lens Epithelial Cells of Thioltransferase Knockout Mouse. Invest. Ophthalmol. Vis. Sci. 49(10): 4497-4505.
    Primary Polymorphonuclear Leukocytes Human BioPORTER Protein Delivery Reagent McLaughlin, N.J., Banerjee, A., Khan, SY, Lieber, JL, Kelher, MR, Gamboni-Robertson, F., Sheppard, FR, Moore, EE, Mierau, GW, Elzi, DJ and Silliman, CC. (2008) Platelet-Activating Factor-Mediated Endosome Formation Causes Membrane Translocation of p67phox and p40phox That Requires Recruitment and Activation of p38 MAPK, Rab5a, and Phosphatidylinositol 3-Kinase in Human Neutrophils. J Immunol 180(12): 8192.
    Primary Neutrophils Human BioPORTER Protein Delivery Reagent McLaughlin, N.J.D., Banerjee, A., Kelher, M.R., Gamboni-Robertson, F., Hamiel, C., Sheppard, F.R., Moore, E.E. and Silliman, C.C. (2006) Platelet-Activating Factor-Induced Clathrin-Mediated Endocytosis Requires beta-Arrestin-1 Recruitment and Activation of the p38 MAPK Signalosome at the Plasma Membrane for Actin Bundle Formation. J. Immunol. 176(11): 7039-7050.
    Primary Adventitial Fibroblasts Rat BioPORTER Protein Delivery Reagent Mounir J. Haurani, M. Eugenia Cifuentes, Alexander D. Shepard, and Patrick J. Pagano (2008) Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II¿Induced Adventitial Myofibroblast Migration. Hypertension 52: 143 - 149. (Catalase)
    Primary Cardiac Myocytes Canine BioPORTER Protein Delivery Reagent Oda, T., Yano, M., Yamamoto, T., Tokuhisa, T., Okuda, S., Doi, M., Ohkusa, T., Ikeda, Y., Kobayashi, S., Ikemoto, N. and Matsuzaki, M. (2005) Defective Regulation of Interdomain Interactions Within the Ryanodine Receptor Plays a Key Role in the Pathogenesis of Heart Failure. Circulation 111: 3400 - 3410. (Delivery of 36-mer peptide)
    Primary Neutrophils Human BioPORTER Protein Delivery Reagent Pestonjamasp, K.N., Forster, C., Sun, C., Gardiner, E.M., Bohl, B., Weiner, O., Bokoch, G.M. and Glogauer, M. (2006) Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis. Blood. 108: 2814-2820.
    Primary Vascular Smooth Muscle Cells Human BioPORTER Protein Delivery Reagent Quasnichka, H., Slater, S.C., Beeching, C.A., Boehm, M., Sala-Newby, G.B. and George, S.J. (2006) Regulation of Smooth Muscle Cell Proliferation by β-Catenin/T-Cell Factor Signaling Involves Modulation of Cyclin D1 and p21 Expression. Circ. Res.99: 1329 - 1337.
    Primary Ventricular Muscle Canine BioPORTER Protein Delivery Reagent Tateishi, H., Yano, M., Mochizuki, M., Suetomi, T., Ono, M., Xu, X., Uchinoumi, H., Okuda, S., Oda, T., Kobayashi, S., Yamamoto, T., Ikeda, Y., Ohkusa, T., Ikemoto, N. and Matsuzaki, M. (2009) Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts Cardiovasc Res. 81(3): 536-545.
    Primary Cortical Neurons Mouse BioPORTER Protein Delivery Reagent Yu, S-W, Andrabi, S.A., Wang, H., Kim, N.S., Poirier, G.G., Dawson, T.M. and Dawson, V.L. (2006) Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc. Natl. Acad. Sci 103: 18314 - 18319.
    Primary Astroglia Rat BioPORTER Protein Delivery Reagent Zassler, B., Blasig, IE and Humpel, C. (2005) Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells. J Neurooncol¿ 71(2): p. 127.
    Primary Capillary Endothelial Cells Rat BioPORTER Protein Delivery Reagent Zassler, B., Blasig, IE and Humpel, C. (2005) Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells. J Neurooncol¿ 71(2): p. 127.
    Primary AML Acute Myelocytic Leukemia Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem. 276: 35103 - 35110.
    Primary Bronchial Epithelial Cells Bronchial Epithelium Human BioPORTER Protein Delivery Reagent Kemp, P.A., Sugar, R.A. and Jackson A.D. (2004) Nucleotide-Mediated Mucin Secretion from Differentiated Human Bronchial Epithelial Cells. Am. J. Respir. Cell Mol. Biol. 31(4): 446-455.
    Primary CML Chronic Myelocytic Leukemia Human BioPORTER Protein Delivery Reagent Zelphati, O., Wang, Y., Kitada, S., Reed, J.C., Felgner, P.L., and Corbeil, J. (2001) Intracellular Delivery of Proteins with a New Lipid-mediated Delivery System. J. Biol. Chem 276: 35103 - 35110.
    Primary Cortical Neurons Primary Cortical Neurons Mouse BioPORTER Protein Delivery Reagent Wang, H., Yu, S-W, Koh, D.W., Lew, J., Coombs, C. Bowers, W., Federoff, H.J., Poirier, G.G., Dawson, T.M. and Dawson, V.L. (2004) Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death. J. Neurosci. 24 (48): 10963-10973.
    Primary Eye Lens Epithelium Eye Lens Rat BioPORTER Protein Delivery Reagent Boyle, D.L., Carman, P. and Takemoto, L. (2002) Translocation of macromolecules into whole rat lenses in culture. Mol. Vis. 8: 226-34.
    Primary Eye Lens Epithelium Eye Lens Rat BioPORTER Protein Delivery Reagent Marques, C., Pereira, P., Taylor, A., Liang, J.N., Reddy, V.N., Szweda, L.I. and Shang, F. (2004) Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells. FASEB J. published 9 July 2004, 10.1096/fj.04-1743fje.
    Primary Microvascular Endothelial Cells Neonatal Dermis Human BioPORTER Protein Delivery Reagent Mammoto, A., Huang, S., Moore, K., Oh, P. and Ingber, D.E. (2004) Role of RhoA, mDia, and ROCK in Cell Shape-dependent Control of the Skp2-p27kip1 Pathway and the G1/S Transition. J. Biol. Chem. 279(25): p. 26323-26330.
    Primary Neutrophils Venous Blood Human BioPORTER Protein Delivery Reagent Diebold, B.A., Fowler, B., Lu, J., Dinauer, M.C. and Bokoch, G.M. (2004)¿Antagonistic Cross-talk between Rac and Cdc42 GTPases Regulates Generation of Reactive Oxygen Species. J. Biol. Chem. 279(27): p. 28136-28142.
    Primary Neutrophils Venous Blood Human BioPORTER Protein Delivery Reagent Gomez-Cambronero, J., Horn, J., Paul, C.C. and Baumann, M.A. (2003) Granulocyte-Macrophage Colony-Stimulating Factor Is a Chemoattractant Cytokine for Human Neutrophils: Involvement of the Ribosomal p70 S6 Kinase Signaling Pathway. J. Immunol. 171: 6846-6855.
    Primary Neutrophils Venous Blood Human BioPORTER Protein Delivery Reagent Rane, M.J., Pan, Y., Singh, S., Powell, D.W., Wu, R., Cummins, T., Chen, Q., McLeish, K.R., and Klein, J.B. (2003) Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation J. Biol. Chem. 278: 27828 - 27835.
    Primary Neutrophils Venous Blood Human BioPORTER Protein Delivery Reagent Zhao, T., Benard, V., Bohl, B.P. and Bokoch, G.M. (2003) The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. J. Clin. Invest. 112: 1732 - 1740.
    Primary Retina Chicken E8 Retina Chicken BioPORTER Protein Delivery Reagent Xu, G., Craig, A.W.B., Greer, P., Miller, M., Anastasiadis, P.Z., Lilien, J. and Balsamo, J. (2004) Continuous association of cadherin with {beta}-catenin requires the non-receptor tyrosine-kinase Fer. J. Cell Sci. 117(15): p. 3207-3219.
    Primary Retinal Growth Cone Retinal Growth Cone Mouse BioPORTER Protein Delivery Reagent Suh, L.H.,. Oster, S.F., Soehrman, S.S., Grenningloh, G.and Sretavan, D.W. (2004) L1/Laminin Modulation of Growth Cone Response to EphBTriggers Growth Pauses and Regulates the Microtubule Destabilizing Protein SCG10. J. Neurosci. 24 (8) 1976-1986.
    rBCEC4 Brain Capillary Endothelial Rat BioPORTER Protein Delivery Reagent Zassler, B., Blasig, IE and Humpel, C. (2005) Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells. J Neurooncol.¿71(2): p. 127.
    SH-SY5Y Neuroblastoma Human BioPORTER Protein Delivery Reagent Yuste, V.J., Sanchez-Lopez, I., Sole, C., Moubarak, R.S.,¿Bayascas, J.R., Dolcet, X., Encinas, M., Susin, S.A. and¿Comella, J.X. (2005)¿The Contribution of Apoptosis-inducing Factor, Caspase-activated DNase, and Inhibitor of Caspase-activated DNase to the Nuclear Phenotype and DNA Degradation during Apoptosis. J. Biol. Chem. 280(42): p. 35670-35683. (Antibody Delivery).
    SH-SY5Y, pgsA-745 bone marrow neuroblast Human BioPORTER Protein Delivery Reagent Claire H. Michel, Satish Kumar, Dorothea Pinotsi, Alan Tunnacliffe, Peter St., George-Hyslop, Eckhard Mandelkow,Eva-Maria Mandelkow, Clemens F. Kaminski and Gabriele S. Kaminski Schierle. Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology. J. Biol. Chem. 2014, 289:956-967.
    UM-SCC-23 Squamous Cell Carcinoma Human BioPORTER Protein Delivery Reagent Shao, H., Cheng, HY, Cook, R.G. and Tweardy, DJ (2003) Identification and Characterization of Signal Transducer and Activator of Transcription 3 Recruitment Sites within the Epidermal Growth Factor Receptor. Cancer Res 63: 3923.

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    Genlantis位于美国加利福尼亚州的圣地亚哥,是基因治疗系统公司的分公司。Genlantis致力于体内和体外诊断蛋白表达工具的研发及高效传递技术的开发。Genlantis为全球的生命科学研究客户生产研发生物学试剂,包括基因传递和质粒DNA的转染试剂(GenePORTER®),哺乳动物细胞siRNA转染试剂(GeneSilencer®),原代神经元细胞的优化转染试剂(NeuroFECT®)和原代神经细胞的转染试剂(NeuroPure®)。此外,我们还是Tap Express®和Xi-Clone® Instant Enzymeless PCR克隆技术的持有者。这些技术使得科学家们可以同时设计成百上千的蛋白,还可把成本控制在理想的范围内;可以使科学家们由复杂的细菌感染比如疟疾,肺结核,炭疽,天花病毒,衣原体,螺杆菌等快速的制备出相应的蛋白。 


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